BC-1215 Size:Contact [email protected] for quotation AML and DLBCL cell lines

Name: BC-1215 Size:Contact sales@xcessbio.com for quotation AML and DLBCL cell lines
Brand: aguscloud.com
SKU: 82386824183
Price: 100.00 USD
Availability: InStock
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SKU: 82386824183

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Description

AML and DLBCL cell lines in a dose- and time-dependent manner

BC-1215 Size:Contact [email protected] for quotation AML and DLBCL cell linesBC 1215 is an inhibitor of F box protein 3 (FBXO3, a ubiquitin E3 ligase component, IC50=0. 9 g mL for IL 1 release). BC 1215 decreases Fbxo3 Fbxl2 interaction and prevents SCFFbxo3 catalyzed Fbxl2 ubiquitination. BC 1215 inhibits the Fbxo3 TRAF activation pathway by destabilizing TRAF1TRAF6. BC 1215, interacts with ApaG to profoundly inhibit secretion of a broad spectrum of TH1 panel cytokines from human PBMC. Product information CAS Number: 1507370

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