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22rv1 and PNT2 cells
6E)-7-[4-(4-fluorophenyl)-2-[N-(²H₃)methylmethanesulfonamido]-6-(propan-2-yl)pyrimidin-5-yl]-3
Smiles: CN1CC2C=CC(=CC=2CC1)NC1N=C(NCCCNC(=O)C2CCC2)C(=CN=1)C1CC1
Solubility: DMSO: 67 mg/mL(198
eCollection 2015 Jan 8
ABT-724 mitocin P-3' 22rv1 and PNT2 cellsABT 724 is a potent and highly selective dopamine D4 receptor agonist with an EC50 of 12. 4 nM for human dopamine D4 receptor. ABT 724 is a potent partial agonist at the rat D4 (EC50 of 14. 3 nM) and the ferret D4 receptor (EC50 of 23. 2 nM). ABT 724 has no effect on dopamine D1, D2, D3, or D5 receptors. ABT 724 could be useful for the treatment of erectile dysfunction and has favorable side effect profile. Product information CAS Number: 70006 24 5