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1-Naphthyl PP1 clib InChiKey: UFPINDDCTUCUSA-ABGUIGEDSA-N

SKU: 44000358097

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Description

InChiKey: UFPINDDCTUCUSA-ABGUIGEDSA-N

Ittyerah R

Doroshow JH

66(16):1768-78

Nat Commun

1-Naphthyl PP1 clib InChiKey: UFPINDDCTUCUSA-ABGUIGEDSA-N1 Naphthyl PP1(1 NA PP 1) is a highly selective and potent pan PKD inhibitor with IC50 of 154. 6 nM,133. 4 nM and 109. 4 nM for PKD1, PKD2 and PKD3, respectively. 1 Naphthyl PP1 is a selective inhibitor of Src family kinases (v Src, c Fyn) and the tyrosine kinase c Abl with IC50 of 1. 0 M, 0. 6 M, 0. 6 M, 18 M and 22 M for v Src, c Fyn, c Abl, CDK2 and CAMK II, respectively. Product information CAS Number: 221243 82 9 Molecular Weight: 317. 39

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