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resulting in the proteasomal degradation of oncogenic client proteins
InChi: InChI=1S/C21H20N2OS3/c1-2-3-12-27(24)21-19(22)18-15(14-8-5-4-6-9-14)13-16(23-20(18)26-21)17-10-7-11-25-17/h4-11
PubMed Central PMCID: PMC5007443
CAS Number: 872511-34-7
It is used in a chemical cocktail of seven small molecules to directly convert human fibroblasts into neuronal cells bypassing a neural progenitor stage
WS6 - β Cell Proliferation Inducer. CAS# 1421227-53-3 Catalog No.:M60097-2S resulting in the proteasomal degradationWS6, CAS No. 1421227 53 3, is a highly potent and selective small molecule that promotes pancreatic cell proliferation in rodent and human primary islets, identified by a high throughput, cell based screening using rodent pancreatic cells. It can induce proliferation of mouse R7T1 cells with an EC50 ~0. 28 M, and induce up to 4% of rat cells and 3% of human cells to proliferate, with a similar EC50 of 0. 4 M. WS6 induces proliferation of primary rat
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