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Istaroxime Catalog No.:M9594-10 CAS Number: 953769-46-5

SKU: 71056489441

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Description

CAS Number: 953769-46-5

The mice treated with 30 mg/kg or 100 mg/kg Pazopanib reveals a significant decrease in tumor burden compared with the mice treated with vehicle or 10 mg/kg Pazopanib

Te Poele RH

Neuroscience

InChiKey: CPUHORIUXPQCHW-UHFFFAOYSA-N

Istaroxime Catalog No.:M9594-10 CAS Number: 953769-46-5Istaroxime, also known as PST 2744, is a positive inotropic agent that mediates its action through inhibition of sodium potassium adenosine triphosphatase (Na+ K+ ATPase). Na+ K+ ATPase inhibition increases intracellular sodium levels, which reverses the driving force of the sodium calcium exchanger, inhibiting calcium extrusion and possibly facilitating calcium entry. Additionally, Istaroxime increases intracellular calcium by improving the efficacy

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