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BAY-985 is a potent and highly selective TBK1/IKKε inhibitor that inhibits the cellular phosphorylation of interferon regulatory factor 3 and displays antiproliferative efficacy in the melanoma cell line SK-MEL-2
4-dihydroxybenzylidene)-2-(naphthalen-2-ylamino)acetohydrazide
Formula: C24H18F3N3O4
DTHIB is a direct and selective heat shock factor 1 (HSF1) inhibitor with a Kd of 160 nM
BAY 43-9006 demonstrates significant activity against several receptor tyrosine kinases involved in neovascularization and tumor progression
meta-iodoHoechst 33258 yrate BAY-985 is a potent andHoechst stains are part of a family of blue fluorescent dyes used to stain DNA. IC50 Value: Target: These Bis benzimides were originally developed by Hoechst AG, which numbered all their compounds so that the dye Hoechst 33342 is the 33342nd compound made by the company. There are three related Hoechst stains: Hoechst 33258, Hoechst 33342, and Hoechst 34580. The dyes Hoechst 33258 and Hoechst 33342 are the ones most commonly used and they have