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40(3-4):222-32
and α2C (8
Formula: C38H69NO13
CAS Number: 79660-72-3
COC1=CC2=C(NC3=CC(Br)=CC=C3)N=CN=C2C=C1OC
AT-406 nbolone acetate 40(3-4):222-32DeBio 1143, also known as AT 406, ARRY 334543and SM 406, is an orally bioavailable inhibitor of IAP (Inhibitor of Apoptosis Protein) family of proteins with potential apoptotic inducing and antineoplastic activity. AT 406 selectively inhibits the biological activity of IAP proteins, including X chromosome linked IAP (XIAP), the cellular IAPs 1 (c IAP1) and 2 (c IAP2) and melanoma inhibitor of apoptosis protein (ML IAP). This may restore and promote