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The hedgehog pathway inhibitor GDC-0449 alters intracellular Ca2+ homeostasis and inhibits cell growth in cisplatin-resistant lung cancer cells
noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity
Azilsartan blocks the vasoconstrictor and aldosteronesecreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in many tissues
Smiles: COC1=CC2=NC=NC(NC3=CC=CC(Cl)=C3F)=C2C=C1OC1CCN(CC(=O)NC)CC1
It has at least 60-fold selectivity as an inhibitor of the KDM2/7 subfamily over the other demethylase subfamily members such as KDM3A
PMSF dol-D6 The hedgehog pathway inhibitor GDC-0449PMSF is an inhibitor of serine proteases such as trypsin and chymotrypsin. It also inhibits cysteine proteases (reversible by reduced thiols) and mammalian acetylcholinesterase. Product information CAS Number: 329 98 6 Molecular Weight: 174. 19 Formula: C7H7FO2S Chemical Name: phenylmethanesulfonyl fluoride Smiles: O=S(=O)(F)CC1C=CC=CC=1 InChiKey: YBYRMVIVWMBXKQ UHFFFAOYSA N InChi: InChI=1S C7H7FO2S c8 11(9,10)6 7 4 2 1 3 5 7 h1 5H,6H2 Technical Data
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