APG-115 Size:Contact [email protected] for quotation InChi: InChI=1S/C21H22O4/c1-13(2)14(3)18-11-16(21(25-4)12-20(18)24)7-10-19(23)15-5-8-17(22)9-6-15/h5-12

InChi: InChI=1S/C21H22O4/c1-13(2)14(3)18-11-16(21(25-4)12-20(18)24)7-10-19(23)15-5-8-17(22)9-6-15/h5-12

Smiles: COC1=CC=CC(CNC2=CC=C(C=C2)S(=O)(=O)NC2=NC3=CC=CC=C3S2)=C1O

Tubercidin inhibits polymerases by incorporating DNA or RNA

Chemical Name: 3'-{2-[2-(3

Schirrmacher E

APG-115 Size:Contact [email protected] for quotation InChi: InChI=1S/C21H22O4/c1-13(2)14(3)18-11-16(21(25-4)12-20(18)24)7-10-19(23)15-5-8-17(22)9-6-15/h5-12APG 115 (AA 115) is an orally active MDM2 protein inhibitor binding to MDM2 protein with IC50 and Ki values of 3. 8 nM and 1 nM, respectively. APG 115 blocks the interaction of MDM2 and p53 and induces cell cycle arrest and apoptosis in a p53 dependent manner. Product information CAS Number: 1818393 16 6 Molecular Weight: 642. 59 Formula: C34H38Cl2FN3O4 Chemical Name: 4 {[(3'R,4'S,5'R) 6'' chloro 4' (3 chloro 2 fluorophenyl) 1' ethyl 2'' oxo 1'',2''