WAY-213613 yl-PEG6-alcohol InChi: InChI=1S/C18H15FN4OS/c1-11-2-3-12-8-13(19)4-5-16(12)23(11)18(24)15-10-25-17(22-15)14-9-20-6-7-21-14/h4-11H

InChi: InChI=1S/C18H15FN4OS/c1-11-2-3-12-8-13(19)4-5-16(12)23(11)18(24)15-10-25-17(22-15)14-9-20-6-7-21-14/h4-11H

ClH/c22-11-16-15(14-6-8-24-9-7-14)10-17(25-21(16)23)20-18(26)2-1-3-19(20)27-12-13-4-5-13

There is a clear dose-dependent reduction in diabetes development in the Paquinimod-treated mice

MSSA: methicillin-sensitive S

Chemical Name: 4-[(2-fluoro-4-methylphenyl)amino]-6-[4-(2-hydroxyethyl)piperazin-1-yl]-7-methoxycinnoline-3-carboxamide

WAY-213613 yl-PEG6-alcohol InChi: InChI=1S/C18H15FN4OS/c1-11-2-3-12-8-13(19)4-5-16(12)23(11)18(24)15-10-25-17(22-15)14-9-20-6-7-21-14/h4-11HWAY 213613 is a potent, selective nonsubstrate reuptake inhibitor of GLT 1 EAAT2 with IC50 of 85 nM EAAT2. It displays 59 and 44 fold selectivity over EAAT1 and EAAT3 (IC50s are 5 and 3. 8 M, respectively). WAY 213613 shows no activity at ionotropic and metabotropic glutamate receptors. It is a potential tool for the elucidation of EAAT2 function. Product information CAS Number: 868359 05 1 Molecular Weight: 415. 19 Formula: C16H13BrF2N2O4 Chemical