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1182/blood-2018-08-868893
GPVI-stimulated platelet aggregation is inhibited in GS-9876-treated monkeys without a concomitant increase in bleeding time (BT)
STF-62247 is a potent Autophagy Inducer
2014 Jul 24
is an inhibitor of p32 mitochondrial protein
PD173074 3295668 1182/blood-2018-08-868893PD173074 is a small molecule FGFR3 selective tyrosine kinase inhibitor (TKI), as a therapeutic modality using eight UC cell lines. PD173074 suppressed cell proliferation remarkably in two cell lines, namely, UM UC 14 and MGHU3, which expressed mutated FGFR3 protein. Cell cycle analysis revealed the growth inhibitory effect of PD173074 was associated with arrest at G(1) S transition in a dose depending manner. In the mouse xenograft models using
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