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P5091 was administered through IV injection at 10 mg/kg twice weekly for 3 weeks
InChiKey: NSEWTSAADLNHNH-TXZJYACMSA-N
5625-100 nM) induces cell cycle arrest and apoptosis at nanomolar concentrations in a series of human myeloma cell lines (HMCL) and prevents outgrowth of a putative CD138+ stem cell population from multiple myeloma (MM) patient-derived peripheral blood mononuclear cells
InChiKey: RFAZNTABYJYOAR-UHFFFAOYSA-N
Erratum in: Org Lett
MN58b - CAS# 203192-01-2 ullone P5091 was administered through IVMN58b, CAS No. 203192 01 2, is a selective choline kinase (CHK) inhibitor. MN58b is a novel anticancer drug that inhibits choline kinase, resulting in inhibition of phosphocholine synthesis. Inhibition of choline kinase by MN58b resulted in altered phospholipid metabolism both in cultured tumor cells and in vivo. Product information CAS Number: 203192 01 2 Molecular Weight: 640. 49 Formula: C32H40Br2N4 Synonym: MN58b MN58b bromide MN 58b Chemical
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