K-Ras ligand-Linker Conjugate 5 G 149 KRIBB11 inhibits HSP70 synthesis through

KRIBB11 inhibits HSP70 synthesis through inhibition of heat shock factor 1 function by impairing the recruitment of positive transcription elongation factor b to the hsp70 promoter

Metronidazole is an antibiotic and antiprotozoal medication

Pyridoxine exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway

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K-Ras ligand-Linker Conjugate 5 G 149 KRIBB11 inhibits HSP70 synthesis throughK Ras ligand Linker Conjugate 5 incorporates a ligand for K Ras recruiting moiety, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K Ras ligand Linker Conjugate 5 can be used in the synthesis of PROTAC K Ras Degrader 1 (HY 129523), which is potent PROTAC K Ras degrader that exhibits 70% degradation efficacy in SW1573 cells. Product information CAS Number: 2378261 85 7 Molecular Weight: 789. 96 Formula: C42H59N7O8