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R428 inhibits Axl with low nanomolar activity and blocked Axl-dependent events
InChiKey: CZZFYGAXGATDNG-UHFFFAOYSA-N
SMND-309 promotes neuron survival through the activation of the PI3K/Akt/CREB-signalling pathway
an antagonist of GABAA receptors
KNK437 (100 μM) inhibits thermotolerance in COLO 320DM cells after the first heat treatment
Damnacanthal Size:Contact [email protected] for quotation R428 inhibits Axl with lowDamnacanthal is an anthraquinone isolated from the root of Morinda citrifolia. Damnacanthal is a highly potent, selective inhibitor of p56lck tyrosine kinase activity. Natural Damnacanthal inhibits p56 lck autophosphorylation and phosphorylation of exogenous substrates with IC50s of 46 nM and 220 nM, respectively. Damnacanthal is a potent inducer of apoptosis with anticancer activity. Damnacanthal also has antinociceptive, anti inflammatory effects in