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BI-9564 - BRD9 Bromodomain Inhibitor. CAS# 1883429-22-8 size:2 mg solid also inhibits 2-HG production in

SKU: 95049401656

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Description

also inhibits 2-HG production in HT1080 and U87MG cells with IC50 ~0

InChi: InChI=1S/C25H20BrN5O3/c1-15(17-10-7-11-18(26)14-17)28-31-25(34)22(27-23(32)16-8-3-2-4-9-16)21-19-12-5-6-13-20(19)24(33)30-29-21/h2-14

The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARgamma expression

115088-06-7

1203494-49-8

BI-9564 - BRD9 Bromodomain Inhibitor. CAS# 1883429-22-8 size:2 mg solid also inhibits 2-HG production inBI 9564, CAS No. 1883429 22 8, is a potent and selective inhibitor of BRD9 and BRD7 bromodomains (Kds = 14. 1 and 239 nM; IC50s = 75 nM and 3. 4 M, respectively). BI 9564 is useful in further exploring BRD9 bromodomain biology in both in vitro and in vivo settings. Selective inhibitors of bromodomain containing protein 9 (BRD9) may have therapeutic potential in the treatment of human malignancies and inflammatory diseases. Product information CAS

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