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PFK-015 (UK-453061) CPI-169 treatment leads to tumor

SKU: 93689273182

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Description

CPI-169 treatment leads to tumor growth inhibition (TGI) of an EZH2 mutant KARPAS-422 DLBCL xenograft

CAS Number: 1474110-21-8

Shuhong Wu

Schimmer AD

CXCL8-induced migration in the non-gradient and the gradient assay is significantly inhibited

PFK-015 (UK-453061) CPI-169 treatment leads to tumorPFK 015 is a potent inhibitor of PFKFB3. The preliminary results in a U87GM xenograft model have shown that PFK 015 has comparable activity to Temozolomide. PFK 015 inhibits glucoseuptake by tumors. Product information CAS Number: 4382 63 2 Molecular Weight: 260. 29 Formula: C17H12N2O Synonym: PFK015 PFK 015 Chemical Name: (2E) 1 (pyridin 4 yl) 3 (quinolin 2 yl)prop 2 en 1 one Smiles: O=C( C=C C1=CC=C2C=CC=CC2=N1)C1C=CN=CC=1 InChiKey: UJJUKZPBUMCSJZ

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