SHP099 was used at 10 µM in vitro and cellular assays
Formula: C26H26ClNO5
Published 2017 Jun 27
49(3):231-9
Bid and survivin are down-regulated
Simvastatin Acyl-β-D-glucuronide itrifluoroacetate SHP099 was used at 10Simvastatin Acyl D glucuronide is a metabolite of Simvastatin. Simvastatin is a competitive inhibitor of HMG CoA reductase with a Ki of 0. 2 nM. Product information CAS Number: 463962 56 3 Molecular Weight: 612. 71 Formula: C31H48O12 Chemical Name: (2S,3S,4S,5R,6S) 6 {[(3R,5R) 7 [(1S,2S,6R,8S,8aR) 8 [(2,2 dimethylbutanoyl)oxy] 8a hydrogenio 2,6 dimethyl 1,2,6,7,8,8a hexahydronaphthalen 1 yl] 3,5 dihydroxyheptanoyl]oxy} 3,4,5 trihydroxyoxane 2