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PubMed PMID: 22284361
Biomed Pharmacother
Epub 2019 Jan 23
Formula: C21H18F3N3O3S2
Cyclosporin-A potently induces highly cardiogenic progenitors from embryonic stem cells
Ku-55933 - CAS# 587871-26-9 0193 PubMed PMID: 22284361KU 55933, CAS No. 587871 26 9, is an ATM inhibitor. KU 55933 blocks the phosphorylation of Akt induced by insulin and insulin like growth factor I in cancer cells that exhibit abnormal Akt activity. Moreover, KU 55933 inhibits cancer cell proliferation by inducing G(1) cell cycle arrest. It does so through the downregulation of the synthesis of cyclin D1, a protein known to be elevated in a variety of tumors. In addition, KU 55933 treatment during
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