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Of 153 cases of leprosy treated with dapsone in Nigeria in 1951, seven cases (4.5%) of sulfone syndrome were observed within two months of starting treatment.10 Over the decades, a variety of medications involved in triggering the DRESS syndrome were identified, especially antiepileptic drugs, antibiotics, antituberculosis drugs, and non-steroidal anti-inflammatory drugs (NSAIDs), among others