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Generally it completely breaks the meta and helps to keep things fresh

You may leaver yourself vulnerable, but red deals damage fast and few things in Magic do it better than goblins

Note that this is a triggered ability that doesn't have a target, so Ghyrson can deal damage to hexproof creatures or players if you have a way to apply the damage, such as a spell that deals one damage to all creatures

Nyx, Realm of the Gods Plane: Nyx Once per turn, you may pay and declare a color

While theres no reason I know of to believe Vindicate will appear in Modern Horizons , if does show up, lordy lordy, thats a game-changer