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4-c]pyridine-3-carboxamide
EGFR (L861Q)
2ClH/c1-22-17-8-7-14(18(12-17)23-2)11-15-5-4-10-21-19(15)16-6-3-9-20-13-16
2-d]pyrimidin-6-yl)methyl)(methyl)amino)pyrimidine-5-carboxamide
857890-39-2
PIK-294 - CAS# 900185-02-6 size:2mg solid 4-c]pyridine-3-carboxamidePIK 294, CAS No. 900185 02 6, is a highly selective inihibitor of the phosphoinositide 3 kinase (PI3K) p110 with an IC50 value of 10 nM compared to IC50 values of 10 M, 490 nM and 160 nM for PI3K , respectively. PIK 294 has been used to help distinguish the unique roles of the various PI3 K isoforms. PIK 294 inhibited both chemokinetic and chemotactic CXCL8 induced migration. Product information CAS Number: 900185 02 6 Molecular Weight: 489. 53