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WSB1 Degrader 1 (compound 4) exhibits potent antimigration efficacy in both KHOS and H460 cell lines with IC50 values of 39
1'-biphenyl]-4-yl}carbamoyl)prop-2-enoic acid
InChi: InChI=1S/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3
PD 144418 potentiates the decrease in 5-hydroxytryptophan caused by Haloperidol in the mesolimbic region
Formula: C21H30Cl2N2O2
RPR-260243 15905 WSB1 Degrader 1 (compound 4)RPR 260243, a potent activator of human ether a go go related gene (hERG), slows deactivation and attenuates inactivation of hERG1 channels. RPR260243 modified HERG currents are inhibited by Dofetilide (IC50=58 nM). RPR260243 displays no activator like effects on other voltage dependent ion channels, including the closely related ERG3 K+ channel. Product information CAS Number: 668463 35 2 Molecular Weight: 510. 50 Formula: C28H25F3N2O4 Chemical Name:
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