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163253-35-8 (Sitafloxacin 1
Smiles: CC1=CC=C(C=NNC(=O)C2=CC=CC=C2OC2C=CC=CC=2)O1
called Olney's lesions (see below)
CAS Number: 865759-25-7
where it inhibits the activity of PI3K and downstream signaling cascades
ANA-12 gin Dihydrochalcone 163253-35-8 (Sitafloxacin 1ANA 12 is aTrkB receptor antagonist. ANA 12 showed direct and selective binding to TrkB and inhibited processes downstream of TrkB without altering TrkA and TrkC functions. Systemic administration of ANA 12 to adult mice decreased TrkB activity in the brain without affecting neuronal survival. Mice administered ANA 12 demonstrated reduced anxiety and depression related behaviors on a variety of tests predictive of anxiolytic and antidepressant