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AZD-2461 - CAS# 1174043-16-3 Catalog No.:M7107-2 24 hours) blocks GTP-KRAS formation

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Description

24 hours) blocks GTP-KRAS formation in H2122

InChi: InChI=1S/C29H32F3N5O3/c1-35-7-9-37(10-8-35)26-6-5-22(21-4-2-3-20(15-21)19-36-11-13-40-14-12-36)16-25(26)34-28(39)23-18-33-27(38)17-24(23)29(30

CAS Number: 49843-98-3

GDC-0941 sensitizes breast cancer to ABT-737 in vitro and in vivo through promoting the degradation of Mcl-1

The discovery of the benzhydroxamate MEK inhibitors CI-1040 and PD 0325901

AZD-2461 - CAS# 1174043-16-3 Catalog No.:M7107-2 24 hours) blocks GTP-KRAS formationAZD 2461, CAS No. 1174043 16 3, is a novel and potent PARP inhibitor with lower affinity to P glycoprotein. AZD2641 is currently in Phase I clinical study. The study is being conducted to see how it may work to treat solid tumors. The main purpose is to establish a safe dosage of the drug and provide additional information on any potential side effects this drug may cause. The study will also assess the blood levels and action of AZD2461 in the body

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