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R-8 is highly selective (>800-fold) versus the other AR subtypes
A small-molecule smoothened agonist prevents glucocorticoid-induced neonatal cerebellar injury
InChi: InChI=1S/C73H129N29O19/c1-5-39(4)55(101-60(112)46(25-26-54(106)107)94-58(110)44(16-9-29-87-70(78)79)92-57(109)43(15-8-28-86-69(76)77)91-56(108)42(75)14-6-7-27-74)66(118)98-49(34-38(2)3)61(113)99-51(36-103)63(115)93-45(17-10-30-88-71(80)81)59(111)95-47(18-11-31-89-72(82)83)67(119)102-33-13-20-53(102)65(117)100-52(37-104)64(116)97-50(35-40-21-23-41(105)24-22-40)62(114)96-48(68(120)121)19-12-32-90-73(84)85/h21-24
EPI-001 can inhibit transactivation of the AR amino-terminal domain (NTD)
ClH/c15-8-11-4-6-12(7-5-11)14-3-1-2-13-9-16-10-17(13)14
PD150606 ropeptide S(Rat) TFA R-8 is highly selective (>800-fold)PD 150606 is a selective, cell permeable non peptide calpain inhibitor with Ki values of 0. 21 M and 0. 37 M for and m calpains respectively, which is neuroprotective. Product information CAS Number: 179528 45 1 Molecular Weight: 306. 12 Formula: C9H7IO2S Chemical Name: 3 (4 iodophenyl) 2 sulfanylprop 2 enoic acid Smiles: OC(=O)C(S)=CC1C=CC(I)=CC=1 InChiKey: DJCVSFWGKYHMKH YVMONPNESA N InChi: InChI=1S C9H7IO2S c10 7 3 1 6(2 4 7)5 8(13)9(11)12 h1
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