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InChi: InChI=1S/C9H10O4/c1-12-8-4-3-6(5-7(8)10)9(11)13-2/h3-5
mouse-adapted H1N1 influenza PR8 virus with 60% survival
18-37)46-28)12-11-27(44-34)33(8)13-14-35(47-33)17-25(38)22(5)30(45-35)23(6)29(42-9)24(7)32(39)40/h19-31
Administration of NCX-1000 to BDL and sham operated rats results in a similar increase of nitrite/nitrate and cGMP concentrations in the liver
CAS Number: 71-30-7
CFI-400945 rexol InChi: InChI=1S/C9H10O4/c1-12-8-4-3-6(5-7(8)10)9(11)13-2/h3-5CFI 400945 is an orally active, potent and selective inhibitor of polo like kinase 4. Polo like kinase 4 (PLK4), a unique member of the Polo like family of kinases, shares little homology with other polo like kinases. PLK4 plays an essential role in centriole duplication. Overexpression of PLK4 overrides the centriole licensing mechanism and results in centriole amplification with multiple procentrioles forming around each parental centriole.