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Solubility: DMSO up to 30 mM
507: a subnanomolar human beta 3 adrenergic receptor agonist
An antibody-drug conjugate targeting the endothelin B receptor for the treatment of melanoma
Formula: C17H11Cl3N2O3
Chemical Name: 4-ethyl-5-methyl-5
AZD8055 - mTOR Inhibitor. CAS# 1009298-09-2 size:2 mg solid Solubility: DMSO up to 30AZD8055, CAS No. 1009298 09 2, is a highly potent, selective and ATP competitive mTOR inhibitor (IC50 = 0. 8 nM). It has >1, 000 fold selectivity against all PI3K isoforms (, , , ) and other members of the PI3K like kinase family (ATM and DNA PK). It has no significant activity against a panel of 260 kinases at concentrations up to 10 M. AZD8055 inhibits the phosphorylation of mTORC1 downstream targets (p70S6K and 4E BP1) as well as phosphorylation of
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