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Pharmacokinetic studies in mice have shown rapid absorption
also known as BIBF 1120
and PDE6 and >2
Formula: C15H10F6N2O3
Chemical Name: 2-(1-{[1-(pyrimidin-2-yl)-1H-imidazol-4-yl]methyl}piperidin-3-yl)-6-(thiophen-2-yl)-1
25(S)-27-hydroxy Cholesterol B3344 R-isomer Pharmacokinetic studies in mice have25(S) 27 hydroxy Cholesterol is a stereoisomer of the endogenous oxysterol 27 hydroxy cholesterol. 27 hydroxy Cholesterol is a sterol 27 hydroxylase mediated cholesterol hydroxylation product involved in activating LXR and LXR and potently suppressing cholesterol biosynthesis [1,2]. Liver X receptors (LXRs) belong to the nuclear receptor superfamily member. LXRs are ligand activated transcription factors containing two LXR isoforms termed as and .
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