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Solubility: DMSO : ≥ 26 mg/mL (64
TJ191 induces the maximum apoptotic rate of 80% after 24 h
[O-]C(=O)CC1=CC=CC=C1NC1C(Cl)=CC=CC=1Cl
Clinical efficacy of anti-emetics is highly correlated with efficacy in the ferret emesis model
Norcholic acid is a normal minorbile C23 bile acid having four side chain and exsits in human urine and meconium
AZ 12080282 dihydrochloride 2653 Solubility: DMSO : ≥ 26AZ 12080282 dihydrochloride is a selective inhibitor of Hh with IC50 value <0. 012 M . It is also reported that AZ 12080282 also has a selective inhibition to p38 with low nanomolar potency . Hedgehog (Hh) signaling plays an important role in a wide variety of developmental processes, including larval body segment development and adult appendages formation. Abnormal activation of Hh pathway may lead to developmental disease by transforming adult stem
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