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Thijssen R
including BCR-ABL
Smiles: CO[C@H]1O[C@H](CO)[C@@H](OC(=O)NC2C=CC(=CC=2)C(=O)OCC)[C@H](OC(=O)NC2=CC3OCOC=3C=C2)[C@H]1OC(=O)NC1=CC2OCOC=2C=C1
Divergent synthesis of multifunctional molecular probes to elucidate the enzyme specificity of dipeptidic gamma-secretase inhibitors
GDC-0941 was used at 1-10 µM in vitro and in cellular assays
5-Hydroxymethyldeoxyuridine - CAS# 5116-24-5 180 Thijssen R5 Hydroxymethyldeoxyuridine, CAS No. 5116 24 5, is a nucleoside analog with anticancer and antiviral activities. It inhibits the replication of murine S180 lung carcinoma cells and Ehrlich ascites mammary carcinoma cells (ED50s = 8. 5 and 4 M, respectively) and multiple human leukemia cell lines (IC50s = 1. 7 5. 8 M). Product information CAS Number: 5116 24 5 Molecular Weight: 258. 23 Formula: C10H14N2O6 Synonym: 5 Hydroxymethyl 2' deoxyuridine
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