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2017 Mar 15
The most common mutation (~90%) in the CFTR gene is a deletion of phenylalanine 508 (F508del)
70(14):1205-10
Bertrand MJM
OPM1 and OPM2 cells) treatment significantly decreases the viability of all the MM cell lines in a time-and dose-dependent manner (IC 50 range for cell lines: 3-7 μM for 48 h)
G-1 ator-1 2017 Mar 15G 1 is a nonsteroidal, high affinity and selective agonist of GPR30 with a Ki of 11 nM. Product information CAS Number: 881639 98 1 Molecular Weight: 412. 28 Formula: C21H18BrNO3 Chemical Name: 1 [(3aS,4R,9bR) 4 (6 bromo 2H 1,3 benzodioxol 5 yl) 3H,3aH,4H,5H,9bH cyclopenta[c]quinolin 8 yl]ethan 1 one Smiles: CC(=O)C1=CC2[C@@H]3C=CC[C@@H]3[C@@H](NC=2C=C1)C1=CC2OCOC=2C=C1Br InChiKey: VHSVKVWHYFBIFJ HKZYLEAXSA N InChi: InChI=1S C21H18BrNO3 c1 11(24)12 5