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72(1):210-9
17(6):1177-1186
Cancer Drug Discovery and Development
The oral formulation was approved on August 22
InChi: InChI=1S/C14H17N3O/c1-3-11-6-12-13(18-11)5-4-10-7-16-17(14(10)12)8-9(2)15/h4-7
JR-AB2-011 Catalog No.:M20491-C 72(1):210-9JR AB2 011 is a selective mTORC2 inhibitor with an IC50 value of 0. 36 M. JR AB2 011 inhibits mTORC2 activity by blocking Rictor mTOR association (Ki: 0. 19 M). JR AB2 011 has anti glioblastoma multiforme (GBM) properties. Product information CAS Number: 2411853 34 2 Molecular Weight: 398. 28 Formula: C17H14Cl2FN3OS Chemical Name: (2Z) N (3,4 dichlorophenyl) 2 [(4 fluorophenyl)imino] 5 methyl 1,3 thiazolidine 3 carboxamide Smiles:
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