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orally active aldose reductase (AR) inhibitor with an IC50 of 3
InChiKey: VMJFTOSOFDEKTM-UHFFFAOYSA-N
Smiles: CC(C)(C)C[C@H]1N[C@H]([C@H](C2=CC=CC(Cl)=C2F)[C@@]21C1=CC=C(Cl)C=C1NC2=O)C(=O)NC1CCC(O)CC1
28)29)19-17(11-13)30-20(31-19)18-12-21(33-32-18)8-4-1-5-9-21/h2-3
with a binding affinity greater than GSH itself and a selectivity for GSTP over 50-fold greater than the GSTM and GSTA classes (Ki=0
rac-Ambrisentan-d3 Methyl Ester Catalog No.:M26463-C orally active aldose reductase (AR)Product information CAS Number: 1329837 75 3 Molecular Weight: 395. 47 Formula: C23H24N2O4 Chemical Name: methyl 2 [(4,6 dimethylpyrimidin 2 yl)oxy] 3 (H)methoxy 3,3 diphenylpropanoate Smiles: [2H]C([2H])([2H])OC(C(OC1N=C(C)C=C(C)N=1)C(=O)OC)(C1C=CC=CC=1)C1C=CC=CC=1 InChiKey: RCOLWOXJIUGEGI GKOSEXJESA N InChi: InChI=1S C23H24N2O4 c1 16 15 17(2)25 22(24 16)29 20(21(26)27 3)23(28 4,18 11 7 5 8 12 18)19 13 9 6 10 14 19 h5 15,20H,1 4H3 i4D3 Technical Data