3-Hydroxy Midostaurin-D5 arteolol Hydrochloride TBK1/IKKε-IN-1 (compound 1) is a

TBK1/IKKε-IN-1 (compound 1) is a dual inhibitor of TANK-binding kinase 1 (TBK1) and IκB kinase-ε (IKKε/IKK-i) with IC50 of 1

NCCOCCOCCOCCS

Chemical Name: 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine

Smiles: C[C@H]1CCCC=CC(=O)C2=C(CC(=O)O1)C=C(O)C=C2O |t:5|

InChi: InChI=1S/C9H8N2OS2/c10-6-3-7(5-1-2-13-4-5)14-8(6)9(11)12/h1-4H

3-Hydroxy Midostaurin-D5 arteolol Hydrochloride TBK1/IKKε-IN-1 (compound 1) is a3 Hydroxy Midostaurin D5 (CGP52421 D5) is a deuterium labeled 3 Hydroxy Midostaurin. 3 Hydroxy Midostaurin is a metabolite of PKC412, which effectively inhibits FMS like tyrosine kinase 3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9. 8 M in culture medium and plasma, respectively. Product information Molecular Weight: 591. 67 Formula: C35H30N4O5 Chemical Name: N ((5R, 7R, 8R, 9S) 14 hydroxy 8 methoxy 9 methyl 16 oxo 6, 7, 8, 9,