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) has antipsychotic-like activity in an amphetamine-induced hyperlocomotion (AHL) rat model
Bcl-2 (IC50=20 µM
4]oxazin-8-yl]-5-fluoro-2-methylpyrimidin-4-yl}hydrazinecarbonyl)-2-(cyclopentylmethyl)ethyl]-N-hydroxyformamide
and potently inhibited the growth of human thyroid cancer cell lines with activating mutations of RET but not of lines without RET mutations
It exhibits only peripheral activity since it does not readily cross the blood-brain barrier
NPEC-caged-(1S, 3R)-ACPD noside Rg1 ) has antipsychotic-like activity inProduct information CAS Number: 1315379 60 2 Molecular Weight: 366. 32 Formula: C16H18N2O8 Chemical Name: (1S,3R) 1 [(E) {hydroxy[1 (2 nitrophenyl)ethoxy]methylidene}amino]cyclopentane 1,3 dicarboxylic acid Smiles: CC(O C( O)=N [C@@]1(C[C@@H](CC1)C(O)=O)C(O)=O)C1=CC=CC=C1N(=O)=O InChiKey: SKBDCZAPZZBWJU XOXYBHGNSA N InChi: InChI=1S C16H18N2O8 c1 9(11 4 2 3 5 12(11)18(24)25)26 15(23)17 16(14(21)22)7 6 10(8 16)13(19)20 h2 5,9 10H,6
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