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4-O-Methyl honokiol (20 μM) increases the expression
InChi: InChI=1S/C11H12BrNO3S/c1-16-11(15)9(6-17)13-10(14)7-2-4-8(12)5-3-7/h2-5
CAS Number: 2111834-61-6
Chemical Name: {[(1S)-1-(chloromethyl)-3-(5-{5-[4-methyl-4-(methyldisulfanyl)pentanamido]-1H-indole-2-amido}-1H-indole-2-carbonyl)-1H
Chemical Name: 2-[(hydrogen phosphonatooxy)methyl]-1-hydroxy-4-(4-octylphenyl)butan-2-aminium
AC-4-130 Catalog No.:M31939-C 4-O-Methyl honokiol (20 μM) increasesAC 4 130 is a potent STAT5 SH2 domain inhibitor. AC 4 130 directly binds to STAT5 and disrupts STAT5 activation, dimerization, nuclear translocation, and STAT5 dependent gene transcription. AC 4 130 induces cell cycle arrest and apoptosis in FLT3 ITD driven leukemic cells. AC 4 130 has anti cancer activity and can efficiently block pathological levels of STAT5 activity in acute myeloid leukemia (AML). Product information CAS Number: 1834571 82 2
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