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Compound E Catalog No.:M13053-2 Smiles: CC1=CC(=CC=C1CCC(O)=O)OCC1=NC(=CS1)C1=CC=CC=C1Cl

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Description

Smiles: CC1=CC(=CC=C1CCC(O)=O)OCC1=NC(=CS1)C1=CC=CC=C1Cl

Smiles: NC1=CC=CC=C1NC(=O)CCCCCCC(=O)NC1C=CC=CC=1

EW-7197 Hydrochloride

PubMed PMID: 25279148

4-tetrahydropyrimidine-5-carboxylic acid

Compound E Catalog No.:M13053-2 Smiles: CC1=CC(=CC=C1CCC(O)=O)OCC1=NC(=CS1)C1=CC=CC=C1ClCompound E is a secretase inhibitor. Compound E bloks amyloid(40), amyloid(42), and Notch secretase cleavage with IC50s of 0. 24, 0. 37, 0. 32 nM, respectively. Product information CAS Number: 209986 17 4 Molecular Weight: 490. 50 Formula: C27H24F2N4O3 Chemical Name: (2S) 2 [2 (3,5 difluorophenyl)acetamido] N [(3S) 1 methyl 2 oxo 5 phenyl 2,3 dihydro 1H 1,4 benzodiazepin 3 yl]propanamide Smiles:

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