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(-)-U-50488 hydrochloride erifosine YM17E inhibits production of [14C]cholesteryloleate

SKU: 22345877385

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Description

YM17E inhibits production of [14C]cholesteryloleate from [14C]oleoyl CoA in a dose-dependent manner in both liver and intestinal microsomes used as enzyme sources

Chowdhury J

InChi: InChI=1S/C12H17N5O/c13-12-16-10-9(14-7-15-10)11(17-12)18-6-8-4-2-1-3-5-8/h7-8H

4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1

20 μM: inhibits inducible nitric oxide synthases (iNOS)

(-)-U-50488 hydrochloride erifosine YM17E inhibits production of [14C]cholesteryloleate( ) U 50488 hydrochloride is a selective agonist for opioid receptor . The opioid receptor (KOR) is a type of opioid receptor for opioid peptide dynorphin and controls addiction. Also, KOR plays an important role in stress, anxiety, anhedonia, depression and increased drug seeking behavior. ( ) U 50488 hydrochloride is a selective KOR agonist . In isolated rat DRG neurons, U 50488 (0. 3 40 M) inhibited voltage independent Ca2+ channel currents. In

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