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InChi: InChI=1S/C27H26F4N2O5/c28-16-6-11-22-20(14-16)25(32(17-7-8-17)23(34)12-13-24(35)36)19-2-1-3-21(19)33(22)26(37)15-4-9-18(10-5-15)38-27(29
suggesting promotion of programmed cell death
15(11):21419-32
In the guinea-pig isolated internal carotid artery
3H2O/c2*1-10(11
IACS-010759 Catalog No.:M20465-C InChi: InChI=1S/C27H26F4N2O5/c28-16-6-11-22-20(14-16)25(32(17-7-8-17)23(34)12-13-24(35)36)19-2-1-3-21(19)33(22)26(37)15-4-9-18(10-5-15)38-27(29IACS 010759 is an orally active, potent mitochondrial complex I of oxidative phosphorylation (OXPHOS) inhibitor. IACS 010759 inhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia (AML) reliant on OXPHOS. IACS 010759 has the potential for relapsed refractory AML and solid tumors research. Product information CAS Number: 1570496 34 2 Molecular Weight: 562. 56 Formula: C25H25F3N6O4S Chemical Name: 4
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