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CHK1-IN-4 Catalog No.:M30036-C CHLA-90: 6

SKU: 15752808396

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Description

CHLA-90: 6

selective and orally active antimicrobial against Helicobacter pylori with an IC50 of 0

XL019 is an orally bioavailable inhibitor of Janus-associated kinase 2 (JAK2) with potential antineoplastic activity

InChi: InChI=1S/C27H29N5O3

3S)-2-[(Z)-[(2R)-2-[(Z)-[(2S)-2-[(Z)-[(2S)-2-[(Z)-{2-[(Z)-{[(2S)-1-[(2S)-1-[(2S)-2-[(Z)-[(2S)-6-amino-1-hydroxy-2-[(Z)-(1-hydroxyethylidene)amino]hexylidene]amino]-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]pyrrolidin-2-yl](hydroxy)methylidene}amino]-1-hydroxyethylidene}amino]-1-hydroxy-2-methyl-3-phenylpropylidene]amino]-1

CHK1-IN-4 Catalog No.:M30036-C CHLA-90: 6CHK1 IN 4 (Compound 3) is a potent checkpoint kinase 1 (chk1) inhibitor, and potently inhibits chk1 phosphorylation in the tumor cells. CHK1 IN 4 has anti tumor activity. Product information CAS Number: 2120398 41 4 Molecular Weight: 444. 29 Formula: C18H18BrN7O2 Chemical Name: 5 ({5 [2 (3 aminopropoxy) 4 bromo 6 methoxyphenyl] 1H pyrazol 3 yl}amino)pyrazine 2 carbonitrile Smiles: COC1=CC(Br)=CC(OCCCN)=C1C1=CC(NC2=CN=C(C=N2)C#N)=NN1 InChiKey:

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