CDK12-IN-3 13774 CO/N=C(/C1=CSC(N)=N1)\C(=O)N[C@H]1[C@H]2SCC(CSC(=O)C3=CC=CO3)=C(C([O-])=O)N2C1=O

CO/N=C(/C1=CSC(N)=N1)\C(=O)N[C@H]1[C@H]2SCC(CSC(=O)C3=CC=CO3)=C(C([O-])=O)N2C1=O

the inhibitory potency of BXA was comparable to the levels seen with H1N1 and H3N2 viruses (Table 3)

and thus inhibits their biological function

7-dimethoxyquinazolin-1-ium chloride methanol solvate and 4-[(3-hydroxyphenyl)amino]-6

Formula: C13H26O4

CDK12-IN-3 13774 CO/N=C(/C1=CSC(N)=N1)\C(=O)N[C@H]1[C@H]2SCC(CSC(=O)C3=CC=CO3)=C(C([O-])=O)N2C1=OCDK12 IN 3 is a potent and selective CDK12 inhibitor with an IC50 of 491 nM in enzymatic assay. Product information CAS Number: 2220184 50 7 Molecular Weight: 470. 52 Formula: C23H28F2N8O Chemical Name: 2 [(2S) 1 (6 {[(6,7 difluoro 1H 1,3 benzodiazol 2 yl)methyl]amino} 9 (propan 2 yl) 9H purin 2 yl)piperidin 2 yl]ethan 1 ol Smiles: CC(C)N1C=NC2C1=NC(=NC=2NCC1NC2=C(C=CC(F)=C2F)N=1)N1CCCC[C@H]1CCO InChiKey: KULPPFCRBINTBS AWEZNQCLSA N InChi: InChI=1S