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2020 Nov 27
Selectively degrades β-catenin over other Wnt signaling pathway components
It has remarkable selectivity over 266 kinases
Chemical Name: 2-(phenylformamido)acetic acid
Chemical Name: (2S)-2-(2-oxopyrrolidin-1-yl)butanamide
XY1 igase Ligand 14 2020 Nov 27XY1 is an inactive, close analog of SGC707 that can be used as the negative control for SGC707. SGC707 is a potent, selective and cell active allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3) with IC50 and Kd of 31 nM and 53 nM, respectively. Product information CAS Number: 1624117 53 8 Molecular Weight: 297. 35 Formula: C17H19N3O2 Chemical Name: 1 (naphthalen 2 yl) 3 [2 oxo 2 (pyrrolidin 1 yl)ethyl]urea Smiles:
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