NVP-CGM097 piride Hydrochloride 31)32/h1-6

31)32/h1-6

ML-792 selectively blocks SAE enzyme activity and total SUMOylation

Association between inflammatory markers and cardiovascular risk factors in women from Kolkata

CAS Number: 938440-64-3

Chemical Name: 4-(2-methyl-1H-imidazol-1-yl)-2

NVP-CGM097 piride Hydrochloride 31)32/h1-6CGM097 is an orally bioavailable HDM2 (human homolog of double minute 2) antagonist with potential antineoplastic activity. Upon oral administration, p53 HDM2 interaction inhibitor CGM097 inhibits the binding of the HDM2 protein to the transcriptional activation domain of the tumor suppressor protein p53. By preventing this HDM2 p53 interaction, the proteosome mediated enzymatic degradation of p53 is inhibited, which may result in the restoration of