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5 μM) with little cytotoxicity toward HEK293 and human primary fibroblast cells
Development of a sphingosine kinase 1 specific small-molecule inhibitor
28-bis(hydroxymethyl)-2
8 μM against HCC cells
with IC50 of 5
Opipramol-d4 13434 5 μM) with little cytotoxicityProduct information CAS Number: 1215716 70 3 Molecular Weight: 367. 52 Formula: C23H29N3O Chemical Name: 2 [4 (3 {2 azatricyclo[9. 4. 0. 0,]pentadeca 1(15),3,5,7,9,11,13 heptaen 2 yl}propyl)piperazin 1 yl](H)ethan 1 ol Smiles: [2H]C([2H])(N1CCN(CCCN2C3=CC=CC=C3C=CC3=CC=CC=C23)CC1)C([2H])([2H])O InChiKey: YNZFUWZUGRBMHL AUZVCRNNSA N InChi: InChI=1S C23H29N3O c27 19 18 25 16 14 24(15 17 25)12 5 13 26 22 8 3 1 6 20(22)10 11 21 7 2 4 9 23(21)26 h1 4,6