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9(5):319-25
1177/1098612X19825701
SQ-11725 D9
Molecular Weight: 286
CAS Number: 862974-25-2
Cinobufotalin Catalog No.:M8397-10 9(5):319-25Cinobufotalin is a steroid glycoside that reduces SRC 3 protein levels in MCF 7 breast cancer cells, Na+ K+ pump activity, viability, and cell attachment of C7 MDCK cells, and expression of the epithelial mesenchymal (EMT) markers E cadherin, vimentin, ZEB1, and Slug in. Cinobufotalin is cytotoxic to A549, H460, and HTB 58 lung cancer cells. In vivo, Cinobufotalin reduces tumor volume and increases survival in an A549 mouse xenograft model. Product
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