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phosphorylation of HER1-3
RG7128 is also a prodrug of PSI-6130
CAS Number: 1227301-51-0
72 h) potently inhibits the proliferation of H23 and Calu-6 non-small cell lung cancer cell lines with a concentration-dependent manner
is a RORγt agonist
(Z)-Mirin Size:Contact [email protected] for quotation phosphorylation of HER1-3Mirin is a small molecule inhibitor of MRN (Mre11, Rad50, and Nbs1) complex. Target: in vitro: Mirin was shown to block Mre11 exonuclease activity and MRN dependent ATM activation, and to inhibit the ionizing radiation induced G2 M checkpoint and homologous recombination in mammalian cells. Mirin inhibition of ATM activation is independent of Mre11 nuclease inhibition since the M(HN)RN and M(HL DV)RN mutant complexes are inhibited equivalently to the