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Rucaparib (AG014699) is an orally active and potent inhibitor of PARP with Ki of 1
InChi: InChI=1S/C34H57N2O4
3-dihydroxypropyl phosphonato]oxy}ethyl)trimethylazanium
DMU-2105 showed a very high level of selectivity towards CYP1B1 with respect to the IC50 values obtained with CYP1A1
Yongseok Choi
Nepicastat Size:Solid 10 mg Rucaparib (AG014699) is an orallyNepicastat, also known as SYN117 and RS 25560 197, is an inhibitor of dopamine beta hydroxylase, an enzyme that catalyzes the conversion of dopamine to norepinephrine. It has been studied as a possible treatment for congestive heart failure, and appears to be well tolerated. As of 2012, clinical trials to assess nepicastat as a treatment for post traumatic stress disorder (PTSD) and cocaine dependence have been completed. In Phase 2 study treatment