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FASCIN-G2 - Fascin Inhibitor. CAS# 1569076-11-4 yamine Pfeiffer (DLBCL)

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Description

Pfeiffer (DLBCL)

ClH/c28-19-4-3-18(20(29)24-19)27-21(30)16-2-1-15(13-17(16)22(27)31)26-11-9-25(10-12-26)14-5-7-23-8-6-14

CAS Number: 21414-42-6

InChi: InChI=1S/C13H23Br2NO3S/c1-20(18

PD173074 also potently inhibits autophosphorylation of FGFR3 in a dose-dependent manner with IC50 of ~5 nM

FASCIN-G2 - Fascin Inhibitor. CAS# 1569076-11-4 yamine Pfeiffer (DLBCL)FASCIN G2, CAS No. 1569076 11 4, is a potent, selective and bioavailable small molecule that inhibits the actin bundling activity of fascin with Kd ~5 20 M. It specifically blocks filopodial formation, tumour cell migration and invasion in vitro. , FASCIN G2 showed very good in vivo efficacy in 4T1 mammary tumour metastasis model and in MDA MB 231 human breast tumour metastasis model. Product information CAS Number: 1569076 11 4 Molecular Weight: 385.

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