PROTAC BRD4 Degrader-12 - CAS# 2417370-90-0 Catalog No.:M35003-C The presence of JW74 in

The presence of JW74 in tumors and plasma is identified by mass spectrometry

Chemical Name: 5-[3-(4-cyclopropanecarbonylphenoxy)propyl]-1H-imidazole

rat cardiac myocyte cells) treatment reduces high glucose-induced resistin and nuclear NFATc expression and increases the phosphorylation of AMPKα in a time-dependent manner

39)7)52-36-33(31(48)30(47)25(18-42)53-36)54-35-32(49)29(46)23(44)19-51-35/h10

Smiles: C1=CC2=CC=CC=C2[O+]=C1C1C=CC=CC=1

PROTAC BRD4 Degrader-12 - CAS# 2417370-90-0 Catalog No.:M35003-C The presence of JW74 inPROTAC BRD4 Degrader 12 (compound 9c) is a PROTAC connected by ligands for von Hippel Lindau and BRD4. PROTAC BRD4 Degrader 12 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0. 39 nM and 0. 24 nM, respectively. Product information CAS Number: 2417370 90 0 Molecular Weight: 1306. 58 Formula: C62H77F2N9O12S4 Chemical Name: (2S,4R) 1 [(2S) 2 (11 {[8 (3,5 difluoropyridin 2 yl) 4