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potent NS3/4A protease inhibitor for the oral treatment of HCV infection
NCI-H441 and A549 in mouse xenografts by 99%
Formula: C17H16BrF3N4O
endothelial cell mitogenesis
arrest the cell cycle
AZD-7762 - CAS# 860352-01-8 Catalog No.:M10890-2 potent NS3/4A protease inhibitor forAZD 7762 is a synthetic small molecule inhibitor of checkpoint kinases (Chks) with potential chemosensitizing activity. AZD7762 binds to and inhibits Chks, which may prevent cell cycle arrest and subsequent nucleotide excision repair in DNA damaged tumor cells, resulting in tumor cell apoptosis. This agent may enhance the cytotoxicity of DNA damaging agents. Chks are protein kinases that regulate either G1 S or G2 M transitions in the cell cycle. In
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